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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN2
All Species:
22.73
Human Site:
S535
Identified Species:
38.46
UniProt:
Q16513
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16513
NP_006247.1
984
112035
S535
V
N
H
S
G
T
F
S
P
Q
A
P
V
P
T
Chimpanzee
Pan troglodytes
XP_001145367
984
112028
S535
V
N
H
S
G
T
F
S
P
Q
A
P
V
P
T
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
S585
C
S
S
P
S
T
I
S
P
P
K
G
C
P
R
Dog
Lupus familis
XP_547295
1021
115999
S572
V
N
H
S
G
T
F
S
P
Q
A
P
V
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWW9
983
111611
S534
V
N
H
S
G
T
F
S
P
Q
T
P
V
P
A
Rat
Rattus norvegicus
O08874
985
112050
S536
V
N
H
S
G
T
F
S
P
Q
T
P
V
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
G567
L
G
L
L
P
P
C
G
S
P
S
S
T
L
S
Chicken
Gallus gallus
XP_422357
1013
114806
S561
V
N
H
S
G
T
F
S
P
Q
A
P
V
P
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700704
970
110327
L528
P
N
N
S
F
S
P
L
A
A
E
T
G
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
R221
P
D
K
Q
Q
P
R
R
S
K
Y
L
N
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
V294
H
K
R
C
Q
R
N
V
A
N
N
C
G
I
N
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
A386
E
A
D
S
S
E
S
A
G
S
N
S
Q
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
E685
I
E
H
S
Q
T
W
E
S
K
D
D
L
M
R
Red Bread Mold
Neurospora crassa
P87253
1142
127954
I637
G
S
T
A
Y
T
S
I
A
S
P
E
A
T
E
Conservation
Percent
Protein Identity:
100
99.6
46.1
92.8
N.A.
94.6
92.6
N.A.
53.9
87
N.A.
76.4
N.A.
28.3
N.A.
27.6
48.4
Protein Similarity:
100
99.9
63.2
94.7
N.A.
97.2
95.3
N.A.
68.2
91.9
N.A.
85
N.A.
42.3
N.A.
43.7
61.3
P-Site Identity:
100
100
26.6
100
N.A.
86.6
86.6
N.A.
0
93.3
N.A.
13.3
N.A.
0
N.A.
0
6.6
P-Site Similarity:
100
100
33.3
100
N.A.
86.6
86.6
N.A.
20
93.3
N.A.
33.3
N.A.
13.3
N.A.
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
27.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
45.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
0
8
22
8
29
0
8
0
22
% A
% Cys:
8
0
0
8
0
0
8
0
0
0
0
8
8
0
0
% C
% Asp:
0
8
8
0
0
0
0
0
0
0
8
8
0
0
0
% D
% Glu:
8
8
0
0
0
8
0
8
0
0
8
8
0
8
8
% E
% Phe:
0
0
0
0
8
0
43
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
0
43
0
0
8
8
0
0
8
15
0
8
% G
% His:
8
0
50
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
0
0
0
0
0
8
8
0
0
0
0
0
8
0
% I
% Lys:
0
8
8
0
0
0
0
0
0
15
8
0
0
0
0
% K
% Leu:
8
0
8
8
0
0
0
8
0
0
0
8
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
50
8
0
0
0
8
0
0
8
15
0
8
0
8
% N
% Pro:
15
0
0
8
8
15
8
0
50
15
8
43
0
50
0
% P
% Gln:
0
0
0
8
22
0
0
0
0
43
0
0
8
8
8
% Q
% Arg:
0
0
8
0
0
8
8
8
0
0
0
0
0
0
15
% R
% Ser:
0
15
8
65
15
8
15
50
22
15
8
15
0
0
15
% S
% Thr:
0
0
8
0
0
65
0
0
0
0
15
8
8
8
22
% T
% Val:
43
0
0
0
0
0
0
8
0
0
0
0
43
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _